Romania's president has said safety regulations seem to have been ignored in a Bucharest nightclub where a fire killed 27 people on Friday night.
Survivors say the fire started after a heavy metal band set off fireworks, causing the ceiling and a pillar to catch alight and producing heavy smoke.
A stampede for the exit followed. More than 140 people are being treated in hospital, some with severe burns.
Romania has declared three days of national mourning.
"I am saddened, but also revolted that a tragedy of this scale could have taken place in Bucharest," President Klaus Iohannis said.
"We already have indications that the legal regulations had not been respected," he said.
"I hope that the authorities manage their inquiry with speed and rigour."
The fire broke out at about 23:00 at the Colectiv club, which was hosting a free rock concert by the band Goodbye to Gravity. Up to 400 people are thought to have been inside.
Some people initially thought the fire was part of the show, survivors said.
Local journalist Sorin Bogdan told the BBC the club was in a converted former factory with two small exit doors, only one of which was possible to open initially.
A witness quoted by Romania's state news agency said terrified concert-goers had to break the second door down to escape.
"People were fainting, they were fainting because of the smoke. It was total chaos, people were trampled," witness Victor Ionescu told local television station Antena 3.
Some 200 people suffered injuries, including from burns and smoke inhalation. Officials have warned that the death toll may rise.
Hundreds of people who responded to appeals for blood donations queued outside hospitals and blood banks on Saturday.
Prime Minister Victor Ponta cut short a visit to Mexico to return to Bucharest.
It is not the first time pyrotechnics used in a nightclub have caused a deadly fire.
A Russian airliner has crashed in central Sinai killing all 224 people on board, Egyptian officials have said.
The Airbus A-321 had just left the Red Sea resort of Sharm el-Sheikh, bound for the Russian city of St Petersburg.
Wreckage was found in the Hasana area and bodies removed, along with the plane's "black box". An official described a "tragic scene" with bodies of victims still strapped to seats.
Egypt's prime minister said no "irregular" activities were to blame.
Sinai has an active militant network, and on Saturday afternoon, jihadis allied to the so-called Islamic State made a claim on social media that they brought down flight KGL9268.
But Russian Transport Minister Maksim Sokolov told Interfax news agency that "such reports cannot be considered true". No evidence had been seen that indicated the plane was targeted, he said.
Egypt's civilian aviation ministry said the plane had been at an altitude of 9,450m (31,000ft) when it disappeared.
Security experts say a plane flying at that altitude would be beyond the range of a shoulder-launched surface-to-air missile (Manpad), which Sinai militants are known to possess.
But the German carrier Lufthansa said it would avoid flying over Sinai "as long as the cause for today's crash has not been clarified". On Saturday evening, Air France said it was following suit.
British Airways and easyJet said their routes were regularly reviewed, but that they had no plans to alter their routes to and from Sharm el-Sheikh.
Russian President Vladimir Putin has declared Sunday a day of mourning.
He has ordered an official investigation into the crash of the flight, and for rescue teams to be sent to the crash site.
Egyptian officials said 214 of the passengers were Russian and three Ukrainian.
Russian authorities say the plane was carrying 217 passengers, 138 of them women and 17 children aged between 2 and 17. Most were tourists. There were seven crew on board.
A commission headed by Mr Sokolov left for Egypt on Saturday afternoon.
A criminal case had been opened against the airline, Kogalymavia, for "violation of rules of flight and preparation for them", Russia's Ria news agency reported.
Yulia Zaitseva said her friends, newlyweds Elena Rodina and Alexander Krotov, were on board.
"We were friends for 20 years," she told AP at a hotel where relatives were meeting near Pulkovo airport in St Petersburg.
"To lose such a friend is like having your hand cut off."
Timeline: the course of flight KGL9268
05:58 Egyptian time (03:58 GMT): flight leaves Sharm el-Sheikh, the Egyptian cabinet says in a statement
06:14 Egyptian time (04:14 GMT): plane fails to make scheduled contact with air traffic control based in Larnaca, Cyprus, according to Sergei Izdolsky, an official with Russia's air transport agency.
06:17 Egyptian time, approx (04:17 GMT): plane comes down over the Sinai peninsula, according to Airbus
11:12 Egyptian time (09:12 GMT): flight had been due to land in St Petersburg's Pulkovo airport
Oksana Golovin, a spokeswoman for Kogalymavia, said the company did not see any grounds to blame human error.
She told a press conference that the pilot had 12,000 hours of flying experience. Kogalymavia did not yet know what caused the crash, she said, but the plane was fully serviced.
Police are reported to be searching the company's offices.
Initially there were conflicting reports about the fate of the plane, some suggesting it had disappeared over Cyprus.
But the office of Egyptian Prime Minister Sharif Ismail confirmed in a statement that a "Russian civilian plane... crashed in the central Sinai".
Officials say up to 50 ambulances have been sent to the scene. Access to the area is strictly controlled by the military.
One official told Reuters news agency that at least 100 bodies had been found.
"I now see a tragic scene," the official said. "A lot of dead on the ground and many died whilst strapped to their seats."
The plane split in two, with one part burning up and the other crashing into a rock, he added.
Image copyrightReuters
Kogalymavia airline
Also known as KolAvia
Founded in 1993
Carried out regular and charter flights to other parts of Russia from the western Siberian towns of Kogalym and Surgut, and helicopter flights for the oil and gas industry
Rebranded as Metrojet in 2012
After takeover by tourism company TH&C in 2013, began flights to international destinations popular with Russian holiday-makers
Currently has fleet of seven Airbus-321s and two Airbus-320s
Live flight tracking service Flight Radar 24's Mikail Robertson told the BBC that the plane started to drop very fast, losing 1,500 metres in one minute before coverage was lost.
Egyptian aviation official Ayman al-Mukadem said the pilot had reported technical difficulties before the plane went missing, the Associated Press reported.
Local weather observations in the vicinity of the rescue scene suggest relatively benign conditions.
Media caption"The details of orders that popped up... were for another person" says M&S customer Dr Bob Price
One user told the BBC he had seen another person's account details when he tried to register a store loyalty card.
"It accepted my registration but then told me i had 9,000 sparks points which i thought was a bit odd," said Mark Hill.
"So, I looked at the account details and despite saying 'hi Mark' , it was quite clearly an account belonging to a female in a different part of the country."
Marks and Spencer has apologised for the error.
"Due to a technical issue, we temporarily suspended our website yesterday evening," an M&S spokesman said.
Image captionOne customer screengrabbed partial details of another user's credit card details
"This allowed us to thoroughly investigate and resolve the issue and quickly restore service for our customers."
It is not yet clear how many people's details were seen by other M&S customers as a result of the fault.
Media captionA 16-year-old pupil dies after being stabbed at Cults Academy in Aberdeen
He added: "A full and thorough inquiry is under way."
First Minister Nicola Sturgeon said on Twitter: "All my thoughts are with the family and friends of the young man who has tragically died at Cults Academy".
'Heartfelt sympathies'
An Aberdeen City Council spokesperson said: "It is with shock and sadness that we can confirm that a pupil of Cults Academy has died following an incident at the school earlier today.
"Our heartfelt sympathies are extended to the friends and family.
"We will be providing support to pupils, teachers, parents and the community in the coming days.
"Police Scotland is on site and they will provide further updates as required."
The school will be closed on Thursday and Friday.
Cults is regarded as one of Aberdeen's more affluent suburbs.
It has 1,050 pupils and is one of Scotland's best-performing secondary schools, serving pupils from age 11 to 18.